Response to C-CAR088 T cell therapy in ITT population
Best overall response, n (%) | Low-dose group | Medium-dose group | High-dose group | Total |
ITT population | n=4 | n=13 | n=14 | n=31 |
ORR | 3 (75.0) | 11 (84.6) | 13 (92.9) | 27 (87.1) |
sCR | 0 (0.0) | 5 (38.5) | 8 (57.1) | 13 (41.9) |
CR | 0 (0.0) | 1 (7.7) | 2 (14.3) | 3 (9.7) |
VGPR | 3 (75.0) | 4 (30.8) | 2 (14.3) | 9 (29.0) |
PR | 0 (0.0) | 1 (7.7) | 1 (7.1) | 2 (6.5) |
SD | 0 (0.0) | 0 (0.0) | 1 (7.1) | 1 (3.2) |
Not evaluable | 1 (25.0) | 2* (15.4) | 0 (0.0) | 3 (9.7) |
*One patient withdrew on week 2 and the other one died on day 3.
CR, complete response; ITT, intention-to-treat; ORR, overall response rate; PR, partial response; sCR, stringent CR; SD, stable disease; VGPR, very good partial response.