Table 4

Response to C-CAR088 T cell therapy in response-evaluable population

Best overall response, n (%)Low-dose groupMedium-dose groupHigh-dose groupTotal
Response-evaluable populationn=3n=11n=14n=28
ORR3 (100.0)11 (100)13 (92.9)27 (96.4)
 sCR0 (0.0)5 (45.5)8 (57.1)13 (46.4)
 CR0 (0.0)1 (9.1)2 (14.3)3 (10.7)
 VGPR3 (100.0)4 (36.4)2 (14.3)9 (32.1)
 PR0 (0.0)1 (9.1)1 (7.1)2 (7.1)
SD0 (0.0)0 (0.0)1 (7.1)1 (3.6)
  • CR, complete response; ORR, overall response rate; PR, partial response; sCR, stringent complete response; SD, stable disease; VGPR, very good partial response.