Baseline patient characteristic and COVID-19 outcomes of the study population
ICI population | |
N=240 (%) | |
Country | |
UK | 47 (19.6) |
Spain | 77 (32.1) |
Italy | 90 (37.5) |
Others | 26 (10.8) |
Sex | |
Female | 78 (32.5) |
Male | 162 (67.5) |
Age | |
<65 years | 90 (37.5) |
≥65 years | 149 (62.1) |
Missing | 1 (0.4) |
Comorbidities | |
No | 55 (22.9) |
Yes | 185 (77.1) |
Primary tumor | |
Lung | 113 (47.1) |
Melanoma | 51 (21.2) |
Others | 76 (31.7) |
Tumor stage | |
Non-advanced | 37 (15.6) |
Advanced | 190 (80.2) |
Missing | 10 (4.2) |
Tumor status at COVID-19 diagnosis | |
Remission/in-response | 52 (21.7) |
Active malignancy | 184 (76.7) |
Missing | 4 (1.7) |
SARS-CoV-2 vaccination status | |
Unvaccinated | 182 (75.8) |
Fully vaccinated | 42 (17.5) |
Partially vaccinated | 3 (1.3) |
Unkown | 13 (5.4) |
COVID-19 outcomes | |
N (rate, 95% CI) | |
Oxygen therapy Missing | 81 (37.6, 29.9 to 46.8) 25 |
COVID-19-specific therapy Missing | 114 (51.6, 42.5 to 61.9) 19 |
Complications from COVID-19 | 73 (30.4, 23.8 to 38.2) |
Hospitalization Missing | 131 (56.2, 47.0 to 66.7) 7 |
ICU admission Missing | 22 (9.4, 5.9 to 14.3) 7 |
30-days case fatality rate Missing | 55 (23.6, 17.8 to 30.7) 7 |
COVID-19 outcomes' rates are provided in bold.
ICI, immune checkpoint inhibitor; ICU, intensive care unit.