Table 2

Demographic characteristics by cohort

CharacteristicCohort 4Cohort 5Cohort 6
N=20N=20N=16
Age (range)50 (22–78)55 (29–77)60.5 (22–83)
 Gender15/513/714/2
 Males/females n/n (%/%)(75/25)(65/35)(70/10)
 ECOG PS 0/111/97/1316/0
 n/n (%/%)(55/45)(35/65)(100/0)
 BRAF V600+7/157/115/11
 (# positive/available samples)(−47%)(−64%)(45%)
Stage
 IIIB007
 IIIC9115
 IV1194
 M1a221
 M1b442
 M1c531
Sites of visceral metastases
 Lung652
 Peritoneal010
 Small bowel021
 Central nervous system200
  • ECOG PS, Eastern Cooperative Oncology Group performance status.