Table 2

Outcome associated with later-line IPI/NIVO

Patients % (n)
IPI/NIVO
 BOR
  CR7.1 (1/14)
  PR42.9 (6/14)
  SD0 (0/14)
  PD50.0 (7/14)
 Maintenance therapy (NIVO)
  Yes35.7 (5/14)
  No64.3 (9/14)
 PFS
  Median (range)5.07 (2.43–NA)
  1-year rate (%) (95% CI)42.9 (23.4 to 78.5)
  2-year rate (%) (95% CI)26.8 (10.9 to 66.0)
 OS
  Median (range)NR (3.75–NA)
  1-year rate (%) (95% CI)64.3 (43.5 to 95.0)
  2-year rate (%) (95% CI)64.3 (43.5 to 95.0)
  3-year rate (%) (95% CI)64.3 (43.5 to 95.0)
 Median follow-up (months) (IQR)18.85 (17.63–22.40)
  • BOR, best overall response; CR, complete response; IPI/NIVO, ipilimumab plus nivolumab; NA, not available; NIVO, nivolumab; NR, not reached; OS, overall survival; PD, progressive disease; PFS, progression-free survival; PR, partial remission; SD, stable disease.