Table 1

Main PROMs used in clinical trials of hematologic and solid tumor

PROMMain focusReference in the ACT field (if any)
SF-36HRQOL (generic, health status)Tam et al11
EQ-5D-5LHRQOL (generic, health status)Elsawy et al 2021
Shah et al 2020
FACT-GHRQOL (cancer-specific)Sidana et al12
EORTC QLQ-C30 (±disease-specific modules)HRQOL (cancer-specific)Elsawy et al
Shah et al
Abramson et al13–15
Visual Analog Scale for pain or other symptomsPain
PROMISHRQOL (global health, cognitive function, pain, sleep disturbance)Mullane et al16
Hospital Anxiety and Depression ScaleAnxiety and depressionUrsu et al17
Inventory of depression and anxiety symptomsAnxiety and depressionRuark et al7
COST-FACITFinancial toxicityCusatis et al18
  • ACT, adoptive cell therapies; COST-FACIT, COmprehensive Score for financial Toxicity-Functional Assessment of Chronic Illness Therapy; EORTC QLQ-C30, European Organization for Research and Treatment of Cancer Quality of life Questionnaire Core 30; EQ-5D-5L, EuroQoL-5 dimension-5 level; FACT-G, Functional Assessment of Cancer Therapy-General; HRQoL, health-related quality of life; PROM, patient-reported outcome measures; PROMIS, Patient-Reported Outcomes Measurement Information System; SF-36, 36-Item Short Form Health Survey.