Baseline values of the different biological parameters in the cohort of patients with metastatic melanoma
| Low vWF:Ag (N=42) | High vWF:Ag (N=41) | Total (N=83) | P value | |
| vWF:Ag (µg/ml) | 25.76 (3.90) | 37.75 (5.95) | 31.68 (7.82) | <0.0001 |
| ADAMTS13 activity (%) | 65.47 (12.09) | 55.87 (18.36) | 60.18 (16.42) | =0.04 |
| D-dimers (mg/L) | 1.38 (1.84) | 3.04 (6.15) | 2.16 (4.46) | >0.05 |
| Platelets (109/L) | 322.55 (120.60) | 308.00 (106.85) | 315.46 (113.61) | >0.05 |
| LDH (U/L) | 396.79 (449.38) | 432.16 (333.31) | 413.35 (397.17) | >0.05 |
| S100 (µg/L) | 0.40 (0.77) | 1.25 (2.19) | 0.81 (1.66) | =0.026 |
| NLR | 3.26 (1.48) | 4.00 (2.07) | 3.63 (182) | >0.05 |
| CRP (mg/L) | 16.58 (24.66) | 33.42 (48.96) | 24.66 (38.96) | >0.05 |
Biological parameters are reported for the entire cohort but also for the different vWF:Ag low and high groups (median cut-off). Data represent mean (±SD). P values of Kruskal-Wallis test between low and high groups are reported.
NLR, neutrophil-to-lymphocyte ratio; vWF, von Willebrand factor.