Table 1

Patient characteristics

CharacteristicN (%) (N=23)
Age, median (range)36 (23–70)
Male15 (65)
Race
 White19 (83)
 Black/African American3 (13)
 Other1 (4)
Baseline KPS, median (range)90 (80–100)
Diagnosis
 Gray zone lymphoma1 (4)
 Hodgkin’s lymphoma20 (87)
 T-cell lymphoma2 (9)
Stage at diagnosis
 I2 (9)
 II6 (26)
 III9 (39)
 IV6 (26)
Number of prior therapies, median (range)7 (3–12)
Prior BV22 (96)
Prior checkpoint inhibitor16 (70)
Prior AutoSCT17 (74)
Prior AlloSCT10 (43)
Active disease at treatment17 (74)
Dose level
 1×108 cells/m23 (13)
 2×108 cells/m220 (87)
Lymphodepletion type
 Bendamustine7 (30)
 Fludarabine/bendamustine16 (70)
CRS status
 Grade 1 CRS4 (17)
 Grade 2 CRS1 (4)
 No CRS18 (78)
Response to CAR-T
 Responder (CR, PR)16 (70)
 Non-responder (SD, PD)7 (30)
  • AlloSCT, allogeneic stem cell transplant; AutoSCT, autologous stem cell transplant; BV, brentuxumab vedotin; CR, complete response; CRS, cytokine release syndrome; KPS, Karnofsky Performance Status; PD, progressive disease; PR, partial response; SD, stable disease.