Table 1

Clinicopathological features of 60 MPE patients and the infiltration levels of C1q⁺ TAMs

Parameters	Group	Cases	C1q⁺ TAMs low	C1q⁺ TAMs high	P value
Gender	Male	30	14	16	1
Gender	Female	30	14	16	1
Age	<60	24	14	10	0.139
Age	≥60	36	14	22	0.139
Tumor type	Adenocarcinoma	50	23	27	0.766
	Squamous carcinoma	7	3	4
	Small cell lung cancer	3	2	1
Smoke	Yes	13	6	7	0.967
Smoke	No	47	22	25	0.967
MPE volume	Low	6	4	2	0.495
	Medium	18	9	9
	High	36	15	21
Pathological stage	IVa	35	18	17	0.382
Pathological stage	IVb	25	10	15	0.382
Tumor burden	Low	39	26	13	<0.0001
Tumor burden	High	21	2	19	<0.0001
Total		60	28	32

P<0.05 represents statistical significance; χ² test.
C1q, component 1q; MPE, malignant pleural effusion; TAM, tumor-associated macrophage .