Table 3

Skin and blood pharmacokinetics following 4 days of topical everyday dosing of Q-2361

Timepoint following dosageConcentration of Q-2361 in the skin (µg/g)Concentration of Q-2361 in the blood (µg/mL)
1 hour37.3±5.0 (n=2)BLQ*
6 hours52.3±2.0 (n=3)BLQ
  • Skin and whole-blood concentrations of Q-2361 expressed as mean±SD.

  • *One sample just above lower limit of quantitation (3.5 ng/mL).

  • BLQ, below the limit of quantitation.