Table 1

Ranges of randomized parameters in RACIPE

ParameterMinimum valueMaximum value
Production rate (G)1100
Degradation rate (k)0.11
Inhibition fold change (λ)0.011
Activating fold change (λ+)1100
Hill’s coefficient (n)16
ThresholdHalf-functional rule: ensures that each regulatory link in the network has approximately 50% chance to be functional
  • RACIPE, random circuit perturbation.