Parameter | Minimum value | Maximum value |
Production rate (G) | 1 | 100 |
Degradation rate (k) | 0.1 | 1 |
Inhibition fold change (λ−) | 0.01 | 1 |
Activating fold change (λ+) | 1 | 100 |
Hill’s coefficient (n) | 1 | 6 |
Threshold | Half-functional rule: ensures that each regulatory link in the network has approximately 50% chance to be functional |
RACIPE, random circuit perturbation.