Table 1

Participant demographics and baseline characteristics

Demographic, n (%)*mCSCC (N=78)
Sex
 Female19 (24.4)
 Male59 (75.6)
Median age71.6 (37–91)
 <65 years22 (28.2)
 ≥65 years56 (71.8)
Race
 White69 (88.5)
 Asian6 (7.7)
 Unknown2 (2.6)
 Black or African American1 (1.3)
Ethnicity
 Not Hispanic or Latino73 (93.6)
 Hispanic or Latino3 (3.8)
 Unknown2 (2.6)
Country/region
 Australia/New Zealand45 (57.7)
 Europe19 (24.4)
 South Africa8 (10.3)
 Thailand6 (7.7)
PD-L1 status
 PD-L1-positive (≥1%)37 (47.4)
 PD-L1-negative18 (23.1)
 Unknown23 (29.5)
ECOG PS
 023 (29.5)
 155 (70.5)
Primary CSCC site
 Head/neck46 (59.0)
 Extremity18 (23.1)
 Trunk9 (11.5)
 Other5 (6.4)
Type of metastatic disease
 Distant52 (66.7)
 Nodal26 (33.3)
Prior cancer-related surgery47 (60.3)
Prior cancer-related radiotherapy51 (65.4)
Prior cancer-related systemic therapy7 (9.0)
  • *Except for median age, which is presented as years (range).

  • CSCC, cutaneous squamous cell carcinoma; ECOG PS, Eastern Cooperative Oncology Group performance status; mCSCC, metastatic CSCC; PD-L1, programmed cell death-ligand 1.