Table 1

Clinicopathological characteristics and treatment of the BCBM patients

n%
Age at time of BCBMMean52 years
SD10.3
Range29–79 years
GenderFemale9799.0
Male11.0
Breast cancer subtype of BMTNBC2626.6
HR+/HER2+1515.3
HR+/HER2−2121.4
HR−/HER2+3636.7
Number of BM sites19192.9
255.1
3 or more22.0
KPS903131.6
70–805051.0
60 or less1717.4
Metastatic sitesFrontal lobe2222.5
Temporal lobe1111.2
Parietal lobe55.1
Occipital lobe1111.2
Cerebellum3232.7
Others1717.3
De novo stage IV breast cancerYes8384.7
No1515.3
Systemic therapy after BM diagnosisYes8485.7
No1414.3
Radiotherapy after BM diagnosisYes7475.5
No2424.5
  • BCBM, breast cancer brain metastases; HER2, human epidermal growth factor receptor 2; HR, hormone receptor; KPS, Karnofsky performance status; TNBC, triple-negative breast cancer.