PAP allelic variants | PSA allelic variants | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Patients | 122T>G | 849C>T | 993T>C | 1146A>G | 48T>G | 54A>C | 84C>T | 237C>T | 304G>A | 394C>A | 536T>C | |
1 | X | X | X | X | X | |||||||
2 | X | X | X | X | ||||||||
3 | X | X | ||||||||||
4 | X | |||||||||||
5 | X | |||||||||||
6 | X | |||||||||||
Non-Responders | 7 | X | X | X | ||||||||
8 | X | X | X | |||||||||
9 | X | |||||||||||
10 | ||||||||||||
11 | ||||||||||||
12 | ||||||||||||
13 | X | X | X | |||||||||
14 | ||||||||||||
15 | ||||||||||||
16 | X | X | ||||||||||
17 | X | X | X | X | ||||||||
18 | X | X | ||||||||||
19 | X | X | X | X | X | |||||||
20 | X | X | ||||||||||
21 | X | X | X | |||||||||
22 | ||||||||||||
23 | X | X | X | X | ||||||||
Immune Responders | 24 | |||||||||||
25 | X | |||||||||||
26 | X | X | X | |||||||||
27 | X | X | X | X | ||||||||
28 | X | |||||||||||
29 | X | X | X | |||||||||
30 | X | X | X | |||||||||
31 | X | X | X | X | ||||||||
32 | ||||||||||||
33 | X | X | X |
Shown are individual SNPs detected among PAP-specific immune non-responding patients (top, 1â13) and PAP-specific immune responding patients (bottom, 14â33). Detected allelic variants are named for their relative position within each gene such that PAP-c.122T>G is the TâG transversion in the 122 nucleotide from the cDNA start site. Detection of an allelic variant is indicated by an X. Bold face indicates synonymous coding mutations and bold face italic indicates non-synonymous coding mutations.