Patients express multiple allelic variations of PAP and PSA genes

PAP allelic variantsPSA allelic variants
Patients122T>G849C>T993T>C1146A>G48T>G54A>C84C>T237C>T304G>A394C>A536T>C
1XXXXX
2XXXX
3XX
4X
5X
6X
Non-Responders7XXX
8XXX
9X
10
11
12
13XXX
14
15
16XX
17XXXX
18XX
19XXXXX
20XX
21XXX
22
23XXXX
Immune Responders24
25X
26XXX
27XXXX
28X
29XXX
30XXX
31XXXX
32
33XXX

Shown are individual SNPs detected among PAP-specific immune non-responding patients (top, 1–13) and PAP-specific immune responding patients (bottom, 14–33). Detected allelic variants are named for their relative position within each gene such that PAP-c.122T>G is the T→G transversion in the 122 nucleotide from the cDNA start site. Detection of an allelic variant is indicated by an X. Bold face indicates synonymous coding mutations and bold face italic indicates non-synonymous coding mutations.