Response and survival in all 19 patients
| Arm | Stage | ELISPOT response (Y/N/NE) | Best response | No. of cycles completed | Time on trial (months) | Months alive from trial start |
|---|---|---|---|---|---|---|
| A | M | Y | SD | 8 | 3.7 | 9.4 |
| A | M | N | PD | 4 | 1.8 | 15.9 |
| A | M | N | SD | 24 | 11.1 | 47.2* |
| A | NED | N | SD | 24 | 12.4 | 32.4* |
| A | NED | N | SD | 24 | 12.2 | 31.9* |
| B | M | Y | PD | 4 | 1.9 | 3.1 |
| B | M | Y | SD | 23 | 12 | 43.2* |
| B | M | Y | PD | 3 | 1.4 | 3.6 |
| B | M | N | SD | 22 | 10 | ?* |
| B | M | N | PD | 4 | 1.8 | 2.2 |
| B | M | NE | PD | 1 | 0.3 | 0.4 |
| B | M | NE | PD | 4 | 1.2 | 1.5 |
| B | M | NE | PD | 4 | 1.8 | 3.0 |
| C | M | Y | PD | 4 | 1.9 | 11.3 |
| C | LA | Y | CR | 81 | 39.3 | 75.4* |
| C | M | Y | PD | 4 | 1.8 | 11.0 |
| C | M | Y | SD | 12 | 6.2 | 48.5* |
| C | M | NE | PD | 3 | 1.2 | 2.0 |
| C | M | NE | PD | 3 | 1.4 | 2.6 |
Abbreviations: NED = No evidence of disease; M = metastatic; LA = locally advanced; Y = Yes; N = No; NE = not evaluable; * = currently alive; ? = patient is known to be alive but had withdrawn consent; Data as of May 22, 2012.