Grade 2 or greater toxicities associated with vaccine

Grade 1Grade 2Grade 3Grade 4
ToxicityNo. (%)No. (%)No. (%)No. (%)
Injection-site reaction11 (53)1 (5)0 (0)0 (0)
 Erythema9 (47)
 Induration6 (32)1 (5)
 Pain3 (16)
 Ecchymosis2 (11)
 Discoloration1 (5)
 Edema1 (5)
 Rash1 (5)
 Reaction NOS1 (5)
Toxicity unrelated to injection site10 (53)3 (16)4 (21)0 (0)
 Pain10 (53)3 (16)2 (11)
 Fatigue10 (53)1 (5)4 (21)
 Anorexia4 (21)0 (0)2 (11)
 Nausea/Vomiting8 (42)0 (0)1 (5)
 Constipation6 (32)2 (11)1 (5)
 Diarrhea3 (16)1 (5)1 (5)