Patient Characteristics, Tumor Survivin Expression, and CD4+ Survivin Specific Precursor Frequency
| Age | Disease Characteristics | Durie Salmon Stage | Prior Regimens | Imid Therapy | IMWG Response | High Risk | Survivin IHC* | Survivin mRNA** | Survivin Specific CD4+ Precursor Frequency (% of CD4) |
|---|---|---|---|---|---|---|---|---|---|
| 67 | IgG lambda | IIB | 1 | yes | VGPR | no | 7 | - | 0.000000 |
| 46 | IgG lambda | IIIA | 1 | no | PR | no | - | - | 0.000000 |
| 69 | IgG kappa | IIA | 1 | yes | PR | no | 8 | - | 0.000052 |
| 67 | IIIA | 2 | yes | yes | 5 | 1.375 | 0.000274 | ||
| 64 | IgG kappa | IA | 2 | no | VGPR | yes | 5 | - | 0.000346 |
| 49 | IgG lambda | IIIB | 1 | yes | VGPR | no | - | - | 0.000349 |
| 56 | IgG kappa | IIIB | 2 | no | PR | no | 7 | 1.248 | 0.000401 |
| 46 | IgA kappa | IA | 2 | no | PR | no | 4 | 0.814 | 0.000466 |
| 57 | IgG kappa | IIIB | 2 | yes | PR | no | 6 | 0.625 | 0.000643 |
| 69 | IgG kappa | IIIA | 1 | yes | PR | yes | - | - | 0.000798 |
| 69 | IgG kappa | IA | 1 | no | VGPR | no | - | - | 0.001007 |
| 62 | IgG lambda | IIIA | 1 | no | PR | no | - | - | 0.001195 |
| 66 | IgG kappa | IA | 2 | no | PR | yes | 4 | 0.481 | 0.001579 |
| 74 | IgA lambda | IIIB | 2 | yes | PR | yes | 2 | 0.226 | 0.002250 |
| 62 | IgG kappa | IIIA | 1 | yes | VGPR | yes | 5 | - | 0.002657 |
| 50 | lambda light chain | IIA | 1 | no | VGPR | no | - | - | 0.006804 |
*Survivin IHC of bone marrow plasma cells by the Allred scoring system. **Survivin mRNA of isolated CD138+ marrow cells normalized to GAPDH.