Survival by subgroup in ITT population

SubgroupMedian OS (95%CI) months1-year survival rate
%no./total no.
Overall11.0 (6.9 – 19.8)45.013/29
Gender
Female13.9 (6.9 – 19.8)53.38/15
Male8.7 (4.7 – 14.6)36.45/14
Performance status
ECOG 010.8 (6.9 – 19.8)43.87/16
ECOG 111.0 (5.1 – 19.8)46.86/13
Metastasis stage
M1a14.6 (10.3 – 14.6)66.72/3
M1b19.8 (1.2 – 19.8)75.03/4
M1c8.8 (6.3 – 14.3)36.48/22
Age
≤60 years9.8 (6.4 – 14.6)30.03/10
>60 years13.9 (6.3 – 19.8)53.110/19
Pre-treatment
111.3 (6.9 - 13.9)46.97/15
≥210.0 (5.1 – 14.6)42.96/14
Patients
Non-progressive14.2 (11.3 – 19.8)72.78/11
Progressive8.4 (5.1 – 11.0)28.15/18

OS = overall survival, ITT = intention to treat, CI confidence interval.