Summary of patient characteristics, including sites of metastatic disease
| Melanoma (%) N=314 | Renal cell carcinoma (%) N=186 | |
|---|---|---|
| Gender | ||
| Male | 187 (60) | 138 (74) |
| Female | 127 (40) | 48 (26) |
| Age | ||
| Mean (SD) | 53.2 (11.9) | 57.3 (9.1) |
| Range | 20 -79 | 30 – 80 |
| ECOG performance status | ||
| 0 | 220 (71) | 136 (73) |
| 1 | 85 (27) | 47 (25) |
| 2 | 7 (2) | 3 (2) |
| Sites of metastatic disease | ||
| Lymph node | 154 (49) | 39 (21) |
| Lung | 181 (58) | 137 (74) |
| Liver | 96 (31) | 31 (17) |
| Bone | 79 (25) | 43 (23) |
| Brain | 47 (15) | 14 (7) |
| Subcutaneous | 69 (22) | 1(1) |
| Number of metastatic sites | ||
| 1 | 42 (13) | 61 (33) |
| 2 | 69 (22) | 50 (27) |
| 3 | 54 (17) | 38 (20) |
| 4 | 149 (48) | 37 (20) |
| Prior treatment | ||
| Nephrectomy | 2 (1) | 162 (87) |
| Radiation | 139 (44) | 41 (22) |
| Chemotherapy | 28 (9) | 8 (4) |
| Immunotherapy | 119 (38) | 9 (5) |
| VEGF TKI | 0 (0) | 11 (6) |
| Other | 71 (23) | 24 (13) |