Recommended standard materials for immune assays

Technology/AssayRecommended Reference Materials
Blood-based assaysCell lines or control PBMC donor samples prepared and cryopreserved following SOP (reference samples)
Immunohistochemistry assaysControl cell lines or tissue specimens (e.g., human tonsil for PD-L1 staining) or cell lines processed and embedded in paraffin (not to be used for interpreting patient data)
RNA/DNA based assays (NGS, TCR/BCR sequencing, gene expression profiling)Synthetic mimic libraries, TCR/BCR DNA synthetic templates, synthetic vectors, company or WHO and NIST references