TNM classification for staging of hepatocellular carcinoma

StageTNM
IT1N0M0
IIT2N0M0
IIIaT3aN0M0
IIIbT3bN0M0
IIIcT4N0M0
IVaAny TN1M0
IVbAny TAny NM1

T1: single tumor without vascular invasion

T2: single tumor with vascular invasion or multiple tumors, none > 5 cm

T3a: multiple tumors > 5 cm

T3b: tumor involving a major branch of the portal or hepatic vein

T4: tumor with direct invasion of adjacent organs other than gallbladder or with perforation of visceral peritoneum

N0: no regional lymph node metastasis

N1: regionallymph node metastasis

M0: no distant metastasis

M1: distant metastasis