T-VEC injection volume is determined by the longest diameter of the lesion(s), up to a maximum of 4 mL at each visit
| Tumor size (longest dimension) | Maximum injection volume |
|---|---|
| >5.0 cm | 4.0 mL |
| >2.5 cm to 5.0 cm | 2.0 mL |
| >1.5 cm to 2.5 cm | 1.0 mL |
| >0.5 cm to 1.5 cm | 0.5 mL |
| ≤0.5 cm | 0.1 mL |