Stimulants currently available for the TruCulture® Whole Blood Collection and Culture system

Description of stimulantTarget
Null TruCulture (TC) tube (TC Tubes Null)Control
Tumor Necrosis factor (TNF)-alpha tube (TC Tubes TNF-α 10 ng/ml)Cytokine
Intron A/Interferon (IFN)-alpha tube (TC Tubes IFN-α)Cytokine
Interferon (IFN)-beta tube (TC Tubes IFN-β)Cytokine
Interleukin (IL)-1beta + TNF-α tube (TC Tubes IL-1β + TNF-α)Cytokine
Intron A/IFN-α + anti-CD3 + anti-CD28 tube (TC Tubes IFN-α + CD3 + CD28)Cytokine
Intron A/IFN-α + Lipopolysaccharide (LPS)-EB (Escherichia coli 0111:B4) high concentration tube (TC Tubes IFN-α + LPS-EB)Cytokine/TLR4 Ligand
Adenosine Triphosphate (ATP) + LPS-EB tube (TC Tubes ATP + LPS-EB)NLRP3 Inflammasome/TLR4 Ligand
Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid (C12-iE-DAP) tube (TC Tubes C12-iE-DAP)NOD Ligand
Lipoarabinomannan (LAM) from M. smegmatis tube (TC Tubes LAM-MS)NOD Ligand
Staphylococcal Enterotoxin B (SEB) tube (TC Tubes SEB)T-Cell
Anti-CD3/CD28 tube (TC Tubes CD3 + CD28)T-Cell
SEB/anti-CD28 tube (TC Tubes SEB + CD28)T-Cell
anti- CD3 tube (TC Tubes CD3)T-Cell
Zymosan (ZYM) tube (TC Tubes ZYM)TLR2 Ligand
Fibroblast-stimulating Lipopeptide (FSL) tube (TC Tubes FSL-1)TLR2 Ligand
Heat killed E. coli 0111:B4 tube (TC Tubes HKEB)TLR2 Ligand
Heat Killed Lactobacillus rhamnosus tube (TC Tubes HKLR)TLR2 Ligand
Polyinosinic:polycytidylic acid (Poly I:C) tube (TC Tubes Poly I:C)TLR3 Ligand
LPS tube (TC Tubes LPS)TLR4 Ligand
LPS-EB high concentration tube (TC Tubes LPS-EB)TLR4 Ligand
LPS + SEB tube (TC Tubes LPS + SEB)TLR4 Ligand/T-Cell
Resiquimod R848 tube (TC Tubes R848)TLR7/8 Ligand
Gardiquimod (GDQ) tube (TC Tubes GDQ)TLR7/8 Ligand
Class A CpG oligonucleotide + LPS-EB high concentration tube (TC Tubes ODN2216 + LPS-EB)TLR9 Ligand