Reported cases of immunotherapy associated AIHA

Case ReportType of immunotherapy usedNo of prior cyclesType of malignancyMediatorIgG or C3Treatment of AIHAImmunotherapy Re-challengeOther possible association for AIHA
Schwab KS. et al. [9]Nivolumab8Metastatic SCC of skinIgG, C3SteroidsNoCLL
Tardy MP. et al. [10]Nivolumab2Hodgkin’s lymphomaIgGSteroidsYes, 6 more injections. No recurrence of AIHANone
Kong BY. et al. [11]Initially Ipilimumab then patient was started on Nivolumab4Metastatic melanomaIgGSteroidsNoPatient had positive direct anti-globulin test before starting Nivolumab.
Palla AR. et al. [12]Nivolumab2Metastatic lung cancerC3SteroidsNoNone
Simeone E. et al. [13]Ipilimumab3Metastatic melanomaUnknownSteroidsUnknownNone
Simeone E. et al. [13]Ipilimumab3Stage III melanomaUnknownSteroidsUnknownNone
Simeone E. et al. [13]Ipilimumab4Metastatic melanomaUnknownSteroidsUnknownNone