Non-hematologic Toxicities

ToxicityGrade 1N (%)Grade 2N (%)Grade 3N (%)Grade 4N (%)Grade 5N (%)
Dyspnea2 (33.3%)2 (33.3%)1 (16.7%)
Respiratory Failure1 (16.7%)1 (16.7%)
Upper Respiratory Infection1 (16.7%)
Cough1 (16.7%)1 (16.7%)
Pneumonia1 (16.7%)
Hallucinations1 (16.7%)
Dehydration1 (16.7%)1 (16.7%)
Hypotension1 (16.7%)1 (16.7%)
Dermatology, Other (Heating pad burn)1 (16.7%)
Pain1 (16.7%)1 (16.7%)1 (16.7%)
Peripheral Neuropathy1 (16.7%)
Hyperglycemia1 (16.7%)
Infection1 (16.7%)
Sore throat1 (16.7%)
Flu-like symptoms1 (16.7%)
Fatigue1 (16.7%)4 (66.7%)
Arthralgia1 (16.7%)
Headache1 (16.7%)
Fever2 (33.3%)
Decreased level of consciousness1 (16.7%)
Nausea/Vomiting1 (16.7%)
Hyponatremia1 (16.7%)
Hypoxia1 (16.7%)
Syncope1 (16.7%)
Rash1 (16.7%)
Injection site reactiona1 (16.7%)
Infection, Other (Lip)b1 (16.7%)
Dizziness1 (16.7%)
Constipation1 (16.7%)
Hypoalbuminemia1 (16.7%)

aAttributed to DRibble vaccine

bAttributed as unlikely related to DRibble vaccine

All other toxicities were attributed as unrelated to DRibble vaccine, but were considered related to docetaxel or underlying disease