Breast cancer related peptides employed in the 9 peptide vaccine and the tetanus peptide adjuvant

AlleleSequenceEpitope
HLA-A1EADPTGHSYMAGE-A1 161–169
EVDPIGHLYMAGE-A3 168–176
HLA-A2KIFGSLAFLHer-2/neu 369–377
YLSGADLNLCEA 571–579*
GLYDGMEHLMAGE-A10 254–262
HLA-A3HLFGYSWYKCEA 27–35
VLRENTSPKHer-2/neu 754–762
SLFRAVITKMAGE-A1 96–104
HLA-A3/HLA-A31ASGPGGGAPRNY-ESO-1 53–62
Tetanus toxoid-derived helper peptide
Binds to multiple class II allelesAQYIKANSKFIGITELp2830–844**

*Asparagine to aspartic acid change at position 576

**An alanine residue was added to the N-terminus to prevent cyclization