Nuclear staining of enadenotucirev in patients with CRC (IT injection vs IV infusion)

CohortPatientTotal number of sectionsNuclear staining (%)
0> 0 ≤ 20> 20 ≤ 40> 40 ≤ 60> 60 ≤ 80> 80 ≤ 100No tumor
A (IT injection)IT02014203183000
IT02031400021110
IT02044210004307
IT03012171400000
IT030228141121000
Total, n (%)147 (100.0)22 (15.0)56 (38.1)10 (6.8)6 (4.1)15 (10.2)31 (21.1)7 (4.8)
B (IV infusion)IV01014903883000
IV0201a2100301170
IV0301700251113687
IV0302b63021994614
IV03032101173000
Totalb, n (%)224 (100.0)0 (0.0)95 (42.4)38 (17.0)28 (12.5)21 (9.4)21 (9.4)21 (9.4)

aPatient did not have surgery until 51 days after the first IV infusion of enadenotucirev

bNumber corrected from data source