Demographics of patients in the discovery and validation populations

Discovery data setValidation data set
Number of patients210150
Age, median (range) years59 (22–90)53 (18–89)
Gender n (%)
 Male117 (56%)94 (63%)
 Female93 (44%)56 (37%)
Objective Response n (%)
 Patient responsive28 (13%)20 (13%)
 Patients non-responsive182 (87%)130 (87%)
One-year Survival n (%)
 Patient alive at one year118 (56%)43 (29%)
 Patient deceased at one year92 (44%)107 (71%)
 Prior chemotherapyNoYes
Stage of disease n (%)
 IIIC13 (6%)5 (3%)
 IV M1A35 (17%)16 (11%)
 IV M1B49 (23%)30 (20%)
 IV M1C113 (54%)99 (66%)
Live in United States n (%)
 U.S.44 (21%)62 (41%)
 Non-U.S.166 (79%)88 (59%)