Total adverse events reported per cancer

DiseaseNumber of PatientsTaken off therapy secondary to toxicityDeath secondary to toxicityElevation AST any gradeElevation AST grade 3–4Elevation ALT any gradeElevation ALT grade 3–4Diarrhea any gradeDiarrhea grade 3–4
HCC31416051304116404
NSCLC1866751043647516122
Melanoma41185482115633179381242320

HCC Hepatocellular Carcinoma, NSCLC Non-small cell lung cancer, AST aspartate aminotransferase, ALT alanine aminotransferase