SRS Response rate at follow-up MRI

TreatmentScan interval, d (range)CRPRStablePD
SRS + pembro(n = 23)57 (39-118)8 (35%)8 (35%)6 (26%)1 (4%)
SRS + ipi(n = 31)53 (41-95)4 (13%)6 (19%)19 (61%)2 (6%)
SRS(n = 27)51 (28-130)1 (4%)5 (19%)18 (67%)3 (11%)

Response assessment adapted from RANO proposal (Lin et al. 2015)

CR = complete response (disappearance of target lesion)

PR = partial response (lesion visible, ≥ 30% decrease in max diameter)

Stable = stable response (lesion visible, < 30% decrease OR <20% increase in max diameter)

PD = progressive disease (lesion visible, ≥ 20% increase in max diameter)