Custom designed Quantigeneâ„¢ gene panel to detect T cell activation and intra-tumoral inflammation

Cell type-specific markersCoinhibitory & CostimulatoryCytokines & ChemokinesImmunosuppressive EnzymesMarkers of T cell activationAngiogenesis; Endothelial activationEMT markersTGFb pathwayHKGs
Cd144632428N05Rik (Vista)Ccl2 (MCP-1)Arg1Cd69Cdh5Cdh1Smad4Gus
Cd3eCd200r1Ccl3 (MIP-1a)Ido1GzmbHif1aEpcamTgfb1Hprt
Cd4Cd274 (PD-L1)Ccl4 (MIP-1b)MpoIfngVcam1FapTgfb2Ppib
CD68Cd40lgCcl5 (RANTES)Nos2VegfaSnai1Tgfb3Rps18
Cd8b1Cd86Csf2 (GM-CSF)Tdo2VegfcTwist1Tgfbr1
Foxp3Havcr2 (TIM3)Cxcl1Icam1 (CD54)VimTgfbr2
Itgam (CD11B)IcosIfna2SeleCspg4
Itgax (CD11C)Lag3Ifnb1
Klrk1Pdcd1 (PD-1)Il10 (CSIF)
Ms4a1Pdcd1lg2 (PD-L2)Il13
Ptprc (CD45)PvrIl17a
Pvrl2Il2
TigitIl4
Timd4 (TIM4)Il5
Tnfrsf18 (GITR)Il6
Tnfrsf4 (OX40)Il9
Tnfrsf9 (4-1BB)Tnf
Tnfsf18 (GITRL)
Tnfsf4
Tnfsf9 (CD137L, 4-1BBL)