Multivariate logistic regression for colitis risk
| IrAEa | ||
|---|---|---|
| Characteristic | OR (95% CI) | P |
| Race (Caucasian) | 5.76 (2.03–16.36) | 0.001 |
| Cancer stage IV | 0.09 (0.03–0.30) | < 0.001 |
| Cancer type (Melanoma) | 1.96 (1.04–3.67) | 0.037 |
| ICPI agent | ||
| Ipilimumab + combination | 2.23 (1.03–4.81) | 0.041 |
| Nivolumab | 0.39 (0.14–1.11) | 0.079 |
| Duration of ICPI treatment | 0.99 (0.99–1.00) | 0.049 |
aRace, cancer stage, cancer type, ICPI agent, and duration of ICPI treatment were included in the multivariate logistic regression for colitis risk