Association of cancer stage and irAE in patients with melanoma or solid tumor
| Cancer stage IIIn = 25 | Cancer stage IVn = 232 | P | |
|---|---|---|---|
| Diarrhea/colitisa | 18 (72.0) | 82 (35.3) | 0.001 |
| IrAE immunosuppressant treatmentb | |||
| Steroid alone | 4 (16.0) | 38 (16.4) | 1.000 |
| Steroid/Infliximab | 12 (48.0) | 23 (9.9) | < 0.001 |
| Mean length of steroid treatment (days, SD) | 59 (33) | 59 (85) | 0.962 |
Abbreviations: irAE, ICPI related adverse event; SD, standard deviation
aTotal 17 patients with diarrhea/colitis had missing staging information
bImmunosuppressant treatment was administrated in total 77 patients