Baseline patient characteristics
| N = 97 | |
|---|---|
| Gender, N (%), Female/Male | 42 (43.2) / 55 (56.7) |
| Age, years, median (range) | 61 (21–85) |
| Number of previous therapies, N (%) | |
| 1 | 25 (25.8) |
| 2 | 48 (49.5) |
| ≥ 3 | 24 (24.7) |
| Central nervous system (CNS) metastasis | 27 (27.8) |
| Baseline lactate dehydrogenase, N (%) | |
| ≤ upper limit of normal (ULN) | 50 (51.5) |
| > ULN | 45 (46.4) |
| Unknown | 2 (2.1) |
| B-RAF, N (%): | |
| Mutation | 38 (39.1) |
| Wild-Type | 54 (55.7) |
| Unknown | 5 (5.2) |