Parameter | Value | Reference |
---|---|---|
Tumor tissue threshold for hypoxia | 0.5750 | Calibrated to match [11] |
Tumor tissue threshold for necrosis | 0.5325 | Calibrated to match [11] |
Oxygen diffusivity | 1 (*) | [39] |
Oxygen transfer rate from vasculature | 5 (*) | [39] |
Oxygen uptake rate by proliferating tumor cells | 1.5 (*) | [39] |
Oxygen uptake rate by hypoxic tumor cells | 1.3 (*) | [39] |
Oxygen uptake rate by tumor microenvironment | 0.12 (*) | [39] |
Oxygen decay rate | 0.35 (*) | [39] |
(*) Value is non-dimensionalized by the diffusivity of oxygen [68] (1 × 10−5 cm2 s−1)