Response rate (RR) by radiologic (preoperative; 6 weeks from baseline) and histologic (6–8 weeks from baseline) assessments

All patients (N = 28)Ipi 3 mg/kg (n = 14)Ipi 10 mg/kg (n = 14)
No. pts.%No. pts.%No. pts.%
Radiologic preoperative RR (WHO; unconfirmed)10 (9 PR, 1CR)36%4 (3 PR, 1 CR)296 (All PR)43
Pathologic complete RR (no viable tumor on histologic assessment)932%536429
Among radiologic responders
• One relapsed and later responded to anti-PD1 antibody therapy
Among complete pathologic responders
• None relapsed to date