Patient demographics and baseline clinical characteristics by dose level

Characteristic2 mg/kg (n = 10)3 mg/kg (n = 20)
Median age, y (range)69 (23–83)65 (22–81)
Male, n (%)8 (80)10 (50)
White, n (%)8 (80)20 (100)
ECOG performance status, n (%)
 04 (40)3 (15)
 16 (60)15 (75)
 22 (10)
Disease stage, n (%)
 I02 (10)
 II1 (10)3 (15)
 III4 (40)3 (15)
 IV5 (50)12 (60)
Prior treatment with radiation therapy, n (%)3 (30)6 (30)
Prior treatment with systemic therapy, n (%)10 (100)20 (100)
 Median number of prior regimens (range)4.5 (1–8)3.5 (1–9)
Prior treatment with surgery, n (%)3 (30)3 (15)
History of cancer(s) other than current cancer, n (%)5 (50)3 (15)