Mean age, years (SD) | 65 (9.88) |
Male Gender | 67 (74) |
ECOG PS |
0 | 34 (41) |
1 | 33 (40) |
> 2 | 15 (18) |
IMDC Risk Group |
Favorable | 12 (14) |
Intermediate | 61 (69) |
Poor | 15 (17) |
Prior Nephrectomy | 67 (97) |
No of prior systemic therapies, median, No. (range) | 2 (1, 6) |
No of prior systemic therapies |
1 | 42 (47) |
2 | 24 (27) |
3 | 16 (18) |
4 | 6 (7) |
> 5 | 2 (2) |
Most common prior systemic therapies |
Sunitinib | 64 (71) |
Pazopanib | 30 (33) |
Axitinib | 35 (39) |
Sites of metastases at baseline |
Brain | 14 (16) |
Bones | 37 (41) |
Lungs | 65 (72) |
Liver | 27 (30) |
Lymph Nodes | 58 (64) |
Pleural | 18 (20) |
Adrenal | 20 (22) |