Female mice | D15 | D49 | |||
Group 1 | Group 2 | Group 1 | Group 2 | ||
Parameters | Unity | Control | EGT | Control | EGT |
White blood cells | 10^3/μl | 6.4 ± 1.7 | 2.9 ± 1.5 | 7.7 ± 2.1 | 6.3 ± 1.0 |
hemoglobin | g/dl | 13.0 ± 0.3 | 10.9 ± 3.5 | 13.8 ± 1.1 | 14.0 ± 1.3 |
Red blood cells | 10^6/μl | 5.5 ± 3.2 | 6.7 ± 2.1 | 8.4 ± 0.8 | 8.4 ± 0.7 |
Hematocrit | % | 26.6 ± 15.3 | 32.9 ± 11.6 | 40.6 ± 4.2 | 40.8 ± 3.9 |
Mean corpuscular volume | fl | 48.7 ± 0.2 | 48.5 ± 2.6 | 48.3 ± 0.3 | 48.4 ± 0.7 |
Platelets | 10^3/μl | 333 ± 180 | 536 ± 297 | 376 ± 6 | 373.8 ± 62.5 |
Mean corpuscular hemoglobin | pg | 28.3 ± 16.0 | 16.2 ± 1.5 | 16.4 ± 0.3 | 16.5 ± 0.3 |
Mean corpuscular hemoglobin concentration | g/dl | 58.4 ± 32.7 | 33.6 ± 4.0 | 34.0 ± 0.7 | 34.2 ± 0.1 |
Male mice | D15 | D49 | |||
Group 1 | Group 2 | Group 1 | Group 2 | ||
Parameters | Unity | Control | EGT | Control | EGT |
White blood cells | 10^3/μl | 5.6 ± 2.3 | 8.0 ± 1.9 | 8.4 ± 0.1 | 7.5 ± 3.4 |
hemoglobin | g/dl | 13.0 ± 2.5 | 14.9 ± 1.0 | 13.9 ± 1.4 | 13.2 ± 0.7 |
Red blood cells | 10^6/μl | 7.6 ± 1.5 | 8.6 ± 0.6 | 8.3 ± 1.1 | 8.0 ± 0.3 |
Hematocrit | % | 36.8 ± 7.3 | 42.5 ± 1.9 | 40.9 ± 3.5 | 38.7 ± 1.3 |
Mean corpuscular volume | fl | 48.5 ± 0.1 | 49.6 ± 1.2 | 49.6 ± 2.6 | 48.3 ± 0.6 |
Platelets | 10^3/μl | 351 ± 6 | 345 ± 112 | 424 ± 62 | 368 ± 61 |
Mean corpuscular hemoglobin | pg | 17.0 ± 0.1 | 17.3 ± 0.4 | 16.8 ± 0.6 | 16.4 ± 0.3 |
Mean corpuscular hemoglobin concentration | g/dl | 35.2 ± 0.3 | 34.9 ± 1.1 | 34.0 ± 0.6 | 34.0 ± 1.1 |
2x25μg of pIL-12 were injected intradermally in the healthy skin of female and male C57Bl/6 mice. Electrotransfection was realized using HV-MV electrical parameters. Hematological parameters (white blood cells, hemoglobin, red blood cells, hematocrit, mean corpuscular volume, platelets, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration) were determined on 2 female and 2 male mice treated with control and 4 female and 3 male mice treated with GET sacrificed at D15 and on 2 female and 2 male mice treated with control and 4 female and 4 male mice treated with GET sacrificed at D49. Values represent mean ± SD