Hematology analysis of male and female mice of both groups at D15 and D49

Female miceD15D49
Group 1Group 2Group 1Group 2
ParametersUnityControlEGTControlEGT
White blood cells10^3/μl6.4 ± 1.72.9 ± 1.57.7 ± 2.16.3 ± 1.0
hemoglobing/dl13.0 ± 0.310.9 ± 3.513.8 ± 1.114.0 ± 1.3
Red blood cells10^6/μl5.5 ± 3.26.7 ± 2.18.4 ± 0.88.4 ± 0.7
Hematocrit%26.6 ± 15.332.9 ± 11.640.6 ± 4.240.8 ± 3.9
Mean corpuscular volumefl48.7 ± 0.248.5 ± 2.648.3 ± 0.348.4 ± 0.7
Platelets10^3/μl333 ± 180536 ± 297376 ± 6373.8 ± 62.5
Mean corpuscular hemoglobinpg28.3 ± 16.016.2 ± 1.516.4 ± 0.316.5 ± 0.3
Mean corpuscular hemoglobin concentrationg/dl58.4 ± 32.733.6 ± 4.034.0 ± 0.734.2 ± 0.1
Male miceD15D49
Group 1Group 2Group 1Group 2
ParametersUnityControlEGTControlEGT
White blood cells10^3/μl5.6 ± 2.38.0 ± 1.98.4 ± 0.17.5 ± 3.4
hemoglobing/dl13.0 ± 2.514.9 ± 1.013.9 ± 1.413.2 ± 0.7
Red blood cells10^6/μl7.6 ± 1.58.6 ± 0.68.3 ± 1.18.0 ± 0.3
Hematocrit%36.8 ± 7.342.5 ± 1.940.9 ± 3.538.7 ± 1.3
Mean corpuscular volumefl48.5 ± 0.149.6 ± 1.249.6 ± 2.648.3 ± 0.6
Platelets10^3/μl351 ± 6345 ± 112424 ± 62368 ± 61
Mean corpuscular hemoglobinpg17.0 ± 0.117.3 ± 0.416.8 ± 0.616.4 ± 0.3
Mean corpuscular hemoglobin concentrationg/dl35.2 ± 0.334.9 ± 1.134.0 ± 0.634.0 ± 1.1

2x25μg of pIL-12 were injected intradermally in the healthy skin of female and male C57Bl/6 mice. Electrotransfection was realized using HV-MV electrical parameters. Hematological parameters (white blood cells, hemoglobin, red blood cells, hematocrit, mean corpuscular volume, platelets, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration) were determined on 2 female and 2 male mice treated with control and 4 female and 3 male mice treated with GET sacrificed at D15 and on 2 female and 2 male mice treated with control and 4 female and 4 male mice treated with GET sacrificed at D49. Values represent mean ± SD