Geographical pattern of immune checkpoint inhibitor-related haemophagocytic lymphohistiocytosis reporting rate

Country of primary sourceTotal number ofICI-related safety reportsNumber of ICI-related HLH safety reportsICI-related HLH reporting rate (%)
France3526140.4
Japan6421110.2
Germany190130.2
Switzerland83010.1
Canada127910.08
US of America24'99880.03

Abbreviations: ICI immune checkpoint inhibitor, HLH haemophagocytic lymphohistiocytosis