Treatment and outcomes (n = 25)

CharacteristicValue
Hospitalization, n (%)15 (60)
Duration of hospitalization, days (IQR)7 (3–11)
Cholecystitis was the reason to stop ICI treatment, n (%)3 (12)
Treatment, n (%)
 Intravenous fluid17 (68)
 Antibiotics18 (72)
 Steroids5 (20)
 Surgical cholecystectomy5 (20)
 Percutaneous drainage8 (32)
Complications, n (%)
 Sepsis2 (8)
 Perforation4 (16)
Restarted ICI therapy after onset, n (%)10 (40)
Recurrent cholecystitis symptoms, n (%)0 (0)
Any-cause death, n (%)a12 (48)

aDeaths recorded were unrelated to cholecystitis. IQR interquartile range, ICI immune checkpoint inhibitor