Association between lipid metabolism markers and immune cells in the microenvironment
| Variable | CD3+ T cells in the CT | CD3+ T cells in the IM | CD8+ T cells in the CT | CD8+ T cells in the IM | Immunoscore | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low | High | P | Low | High | P | Low | High | P | Low | High | P | Low | High | P | ||
| CHO | 4.97 (1.91–15.30) | 4.90 (1.97–10.28) | 0.801 | 5.00 (1.91–15.30) | 4.82 (1.97–10.28) | 0.487 | 4.88 (2.92–15.30) | 4.88 (1.91–14.97) | 0.796 | 4.93 (1.97–10.28) | 4.86 (1.91–15.30) | 0.990 | 4.98 (1.91–15.30) | 4.80 (1.97–10.28) | 0.386 | |
| TG | 1.08 (0.44–4.83) | 1.15 (0.52–5.82) | 0.959 | 1.12 (0.44–4.83) | 1.13 (0.52–5.82) | 0.797 | 1.07 (0.53–4.92) | 1.14 (0.44–5.82) | 0.386 | 1.13 (0.52–5.82) | 1.10 (0.44–3.76) | 0.365 | 1.09 (0.44–4.92) | 1.13 (0.52–5.82) | 0.986 | |
| HDL-C | 1.13 (0.59–2.73) | 1.18 (0.30–2.19) | 0.475 | 1.18 (0.59–2.73) | 1.14 (0.30–2.17) | 0.410 | 1.18 (0.68–2.73) | 1.13 (0.30–2.43) | 0.364 | 1.14 (0.30–2.19) | 1.17 (0.59–2.73) | 0.627 | 1.18 (0.59–2.73) | 1.14 (0.30–2.17) | 0.679 | |
| LDL-C | 3.06 (0.77–13.48) | 3.10 (0.80–126.10) | 0.758 | 3.04 (0.77–13.48) | 3.12 (0.80–126.10) | 0.861 | 3.05 (0.77–126.10) | 3.01 (0.80–13.48) | 0.819 | 3.13 (0.80–126.10) | 3.00 (0.77–13.48) | 0.735 | 3.13 (0.77–126.10) | 3.00 (0.80–8.56) | 0.394 | |
| ApoA1 | 1.17 (0.58–2.06) | 1.24 (0.44–2.11) | 0.022 | 1.18 (0.58–1.77) | 1.26 (0.44–2.11) | 0.002 | 1.21 (0.58–2.11) | 1.18 (0.44–2.06) | 0.192 | 1.20 (0.44–2.06) | 1.19 (0.63–2.11) | 0.498 | 1.19 (0.58–2.06) | 1.22 (0.44–2.11) | 0.280 | |
| ApoB | 0.97 (0.32–2.80) | 0.98 (0.39–2.08) | 0.828 | 0.97 (0.32–2.80) | 0.97 (0.44–2.11) | 0.929 | 0.97 (0.39–1.69) | 0.97 (0.32–2.80) | 0.408 | 0.97 (0.39–2.08) | 0.97 (0.32–2.80) | 0.832 | 0.98 (0.32–2.80) | 0.96 (0.39–2.08) | 0.801 | |
ApoA1 apolipoprotein A1, ApoB apolipoprotein B, CHO cholesterol, CT core of the tumor, HDL high-density lipoprotein, IM invasive margin, LDL low-density lipoprotein, TG triglyceride