Adaptive immunity

Saponin-based adjuvants enhance antigen cross-presentation in human CD11c⁺ CD1c⁺ CD5⁻ CD163⁺ conventional type 2 dendritic cells
Nataschja I Ho, Lisa G M Huis in 't Veld, Jesper van Eck van der Sluijs, Branco M H Heuts, Maaike W G Looman, Esther D Kers-Rebel, Koen van den Dries, Harry Dolstra, Joost H A Martens, Willemijn Hobo, Gosse J Adema

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007082; DOI: 10.1136/jitc-2023-007082
Dual receptor T cells mediate effective antitumor immune responses via increased recognition of tumor antigens
Hyun J Jang, Christine Caron, Calvin K Lee, Lu Wang, Burhan Jama, Jack D Bui, Gerald P Morris

Journal for ImmunoTherapy of Cancer May 2023, 11 (5) e006472; DOI: 10.1136/jitc-2022-006472
Functional tumor cell-intrinsic STING, not host STING, drives local and systemic antitumor immunity and therapy efficacy following cryoablation
Mohammad Alshebremi, Suzanne L Tomchuck, Jay T Myers, Daniel T Kingsley, Saada Eid, Muta Abiff, Melissa Bonner, Shahrazad T Saab, Sung Hee Choi, Alex Yee-Chen Huang

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e006608; DOI: 10.1136/jitc-2022-006608
Antitumor immunity as the basis for durable disease-free treatment-free survival in patients with metastatic urothelial cancer
Jonathan Anker, Sumanta K Pal, Seunghee Kim-Schulze, Huan Wang, Rebecca Halperin, Andrew Uzilov, Naoko Imai, Shingo Eikawa, Takuro Saito, Robert Sebra, Noah M Hahn, Manishkumar Patel, Jingjing Qi, Hui Xie, Nina Bhardwaj, Sacha Gnjatic, Matthew D Galsky

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007613; DOI: 10.1136/jitc-2023-007613
Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions
Roeland Lameris, Adam Shahine, Myrthe Veth, Bart Westerman, Dale I Godfrey, David Lutje Hulsik, Patricia Brouwer, Jamie Rossjohn, Tanja D de Gruijl, Hans J van der Vliet

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007631; DOI: 10.1136/jitc-2023-007631
C-reactive protein impairs immune response of CD8⁺ T cells via FcγRIIb-p38MAPK-ROS axis in multiple myeloma
Jinxing Jiang, Ziyi Peng, Junying Wang, Mengping Chen, Yike Wan, Honghui Huang, Zhiqiang Liu, Jingya Wang, Jian Hou

Journal for ImmunoTherapy of Cancer Oct 2023, 11 (10) e007593; DOI: 10.1136/jitc-2023-007593
Ablative radiation alone in stage I lung cancer produces an adaptive systemic immune response: insights from a prospective study
Khinh Ranh Voong, Peter B Illei, Bradley Presson, Dipika Singh, Zhen Zeng, Mara Lanis, Russell K Hales, Chen Hu, Phuoc T Tran, Christos Georgiades, Cheng Ting Lin, Jeffrey Thiboutout, Julie R Brahmer, Patrick M Forde, Jarushka Naidoo, Valsamo Anagnostou, Kellie N Smith

Journal for ImmunoTherapy of Cancer Oct 2023, 11 (10) e007188; DOI: 10.1136/jitc-2023-007188
Naive T cells inhibit the outgrowth of intractable antigen-activated memory T cells: implications for T-cell immunotherapy
Sandhya Sharma, Mae Woods, Naren U Mehta, Tim Sauer, Kathan S Parikh, Michael Schmueck-Henneresse, Huimin Zhang, Birju Mehta, Malcolm K Brenner, Helen E Heslop, Cliona M Rooney

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006267; DOI: 10.1136/jitc-2022-006267
Severe cytopenia after CD19 CAR T-cell therapy: a retrospective study from the EBMT Transplant Complications Working Party
Olaf Penack, Christophe Peczynski, Christian Koenecke, Emmanuelle Polge, Andrea Kuhnl, Nathalie Fegueux, Michael Daskalakis, Nicolaus Kröger, Peter Dreger, Caroline Besley, Urs Schanz, Adrian Bloor, Arnold Ganser, Edouard Forcade, Lucia López Corral, Jakob R Passweg, Urban Novak, Ivan Moiseev, Hélène Schoemans, Grzegorz W Basak, Christian Chabannon, Anna Sureda, Dina Averbuch, Bertram Glass, Rafael de la Camara, Zinaida Peric

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006406; DOI: 10.1136/jitc-2022-006406
Intratumor childhood vaccine-specific CD4⁺ T-cell recall coordinates antitumor CD8⁺ T cells and eosinophils
Michael C Brown, Georgia M Beasley, Zachary P McKay, Yuanfan Yang, Annick Desjardins, Dina M Randazzo, Daniel Landi, David M Ashley, Darell D Bigner, Smita K Nair, Matthias Gromeier

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006463; DOI: 10.1136/jitc-2022-006463

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