Adjuvants

STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation
Takashi Nakamura, Takanori Sato, Rikito Endo, Shun Sasaki, Naomichi Takahashi, Yusuke Sato, Mamoru Hyodo, Yoshihiro Hayakawa, Hideyoshi Harashima

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002852; DOI: 10.1136/jitc-2021-002852
Escherichia coli adhesin protein-conjugated thermal responsive hybrid nanoparticles for photothermal and immunotherapy against cancer and its metastasis
Juyoung Hwang, Wei Zhang, Hae-Bin Park, Dhananjay Yadav, Yong Hyun Jeon, Jun-O Jin

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002666; DOI: 10.1136/jitc-2021-002666
Anticoagulation therapy promotes the tumor immune-microenvironment and potentiates the efficacy of immunotherapy by alleviating hypoxia
Jeong Uk Choi, Na Kyeong Lee, Hyungseok Seo, Seung Woo Chung, Taslim A Al-Hilal, Seong Jin Park, Seho Kweon, Nuri Min, Sang Kyoon Kim, Seohyun Ahn, Uk-Il Kim, Jin Woo Park, Chang-Yuil Kang, In-San Kim, Sang Yoon Kim, Kyungjin Kim, Youngro Byun

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002332; DOI: 10.1136/jitc-2021-002332
Phase I/II trial of a long peptide vaccine (LPV7) plus toll-like receptor (TLR) agonists with or without incomplete Freund’s adjuvant (IFA) for resected high-risk melanoma
Sapna P Patel, Gina R Petroni, Jason Roszik, Walter C Olson, Nolan A Wages, Kimberly A Chianese-Bullock, Mark Smolkin, Nikole Varhegyi, Elizabeth Gaughan, Kelly T Smith, Kathleen Haden, Emily H Hall, Sacha Gnjatic, Patrick Hwu, Craig L Slingluff

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e003220; DOI: 10.1136/jitc-2021-003220
Costimulation of γδTCR and TLR7/8 promotes Vδ2 T-cell antitumor activity by modulating mTOR pathway and APC function
Huaishan Wang, Hui Chen, Shujing Liu, Jie Zhang, Hezhe Lu, Rajasekharan Somasundaram, Robin Choi, Gao Zhang, Lingling Ou, John Scholler, Shifu Tian, Liyun Dong, Guo Yeye, Lili Huang, Thomas Connelly, Ling Li, Alexander Huang, Tara C Mitchell, Yi Fan, Carl H June, Gordon B Mills, Wei Guo, Meenhard Herlyn, Xiaowei Xu

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003339; DOI: 10.1136/jitc-2021-003339
Immunogenicity in humans of a transdermal multipeptide melanoma vaccine administered with or without a TLR7 agonist
Max O Meneveau, Gina R Petroni, Elise P Salerno, Kevin T Lynch, Mark Smolkin, Elizabeth Woodson, Kimberly A Chianese-Bullock, Walter C Olson, Donna Deacon, James W Patterson, William W Grosh, Craig L Slingluff

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002214; DOI: 10.1136/jitc-2020-002214
Very small size proteoliposomes abrogate cross-presentation of tumor antigens by myeloid-derived suppressor cells and induce their differentiation to dendritic cells
Audry Fernández, Liliana Oliver, Rydell Alvarez, Arletty Hernández, Judith Raymond, Luis E Fernández, Circe Mesa

Journal for ImmunoTherapy of Cancer Dec 2014, 2 (1) 5; DOI: 10.1186/2051-1426-2-5
In situ immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy
Yinwen Cheng, Caitlin D Lemke-Miltner, Wattawan Wongpattaraworakul, Zhaoming Wang, Carlos H F Chan, Aliasger K Salem, George J Weiner, Andrean L Simons

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e000940; DOI: 10.1136/jitc-2020-000940
Nanoemulsion adjuvantation strategy of tumor-associated antigen therapy rephrases mucosal and immunotherapeutic signatures following intranasal vaccination
Chung-Hsiung Huang, Chiung-Yi Huang, Hui-Min Ho, Ching-Hung Lee, Pang-Ti Lai, Suh-Chin Wu, Shih-Jen Liu, Ming-Hsi Huang

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e001022; DOI: 10.1136/jitc-2020-001022
Poly-IC enhances the effectiveness of cancer immunotherapy by promoting T cell tumor infiltration
Hussein Sultan, Juan Wu, Valentyna I Fesenkova, Aaron E Fan, Diane Addis, Andres M Salazar, Esteban Celis

Journal for ImmunoTherapy of Cancer Sep 2020, 8 (2) e001224; DOI: 10.1136/jitc-2020-001224

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