Antibodies

Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy
Tsung-Yi Lin, Jeong A Park, Alan Long, Hong-Fen Guo, Nai-Kong V Cheung

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e003114; DOI: 10.1136/jitc-2021-003114
First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid tumors and lymphomas
Sarina A Piha-Paul, Ravit Geva, Tira J Tan, Darren WT Lim, Cinta Hierro, Toshikiko Doi, Osama Rahma, Alexander Lesokhin, Jason John Luke, Javier Otero, Lisa Nardi, Angad Singh, Alexandros Xyrafas, Xinhui Chen, Jennifer Mataraza, Philippe L Bedard

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002863; DOI: 10.1136/jitc-2021-002863
GD2-directed bispecific trifunctional antibody outperforms dinutuximab beta in a murine model for aggressive metastasized neuroblastoma
Felix Zirngibl, Sara M Ivasko, Laura Grunewald, Anika Klaus, Silke Schwiebert, Peter Ruf, Horst Lindhofer, Kathy Astrahantseff, Lena Andersch, Johannes H Schulte, Holger N Lode, Angelika Eggert, Kathleen Anders, Patrick Hundsdoerfer, Annette Künkele

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002923; DOI: 10.1136/jitc-2021-002923
Determinants of response to daratumumab in Epstein-Barr virus-positive natural killer and T-cell lymphoma
Nurulhuda Mustafa, Adina Huey Fang Nee, Jing Yuan Chooi, Sabrina Hui Min Toh, Tae-Hoon Chung, Viknesvaran Selvarajan, Shuangyi Fan, Siok Bian Ng, Michelle Poon, Esther Chan, Joanne Lee, Yen Lin Chee, Anand D Jeyasekharan, Longen Zhou, Jennifer Yang, Wee Joo Chng

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002123; DOI: 10.1136/jitc-2020-002123
T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia
Sayed Shahabuddin Hoseini, Mallika Vadlamudi, Madelyn Espinosa-Cotton, Hoa Tran, Yi Feng, Hong-fen Guo, Hong Xu, Irene Cheung, Nai-Kong V Cheung

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002509; DOI: 10.1136/jitc-2021-002509
INfluenza Vaccine Indication During therapy with Immune checkpoint inhibitors: a multicenter prospective observational study (INVIDIa-2)
Melissa Bersanelli, Diana Giannarelli, Ugo De Giorgi, Sandro Pignata, Massimo Di Maio, Alberto Clemente, Elena Verzoni, Raffaele Giusti, Marilena Di Napoli, Giuseppe Aprile, Paola Ermacora, Annamaria Catino, Vieri Scotti, Francesca Mazzoni, Pamela Francesca Guglielmini, Antonello Veccia, Marco Maruzzo, Ernesto Rossi, Francesco Grossi, Chiara Casadei, Corrado Ficorella, Vincenzo Montesarchio, Francesco Verderame, Mimma Rizzo, Giorgia Guaitoli, Lucia Fratino, Caterina Accettura, Manlio Mencoboni, Fable Zustovich, Cinzia Baldessari, Saverio Cinieri, Andrea Camerini, Letizia Laera, Mariella Sorarù, Paolo Andrea Zucali, Valentina Guadalupi, Francesco Leonardi, Marcello Tiseo, Michele Tognetto, Francesco Di Costanzo, Carmine Pinto, Giorgia Negrini, Antonio Russo, Maria R Migliorino, Marco Filetti, Sebastiano Buti

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002619; DOI: 10.1136/jitc-2021-002619
Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas
Claudia Manuela Arnone, Vinicia Assunta Polito, Angela Mastronuzzi, Andrea Carai, Francesca Camassei Diomedi, Laura Antonucci, Lucia Lisa Petrilli, Maria Vinci, Francesco Ferrari, Elisa Salviato, Marco Scarsella, Cristiano De Stefanis, Gerrit Weber, Concetta Quintarelli, Biagio De Angelis, Malcolm K Brenner, Stephen Gottschalk, Valentina Hoyos, Franco Locatelli, Ignazio Caruana, Francesca Del Bufalo

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e001930; DOI: 10.1136/jitc-2020-001930
Improving selection of patients with metastatic colorectal cancer to benefit from cetuximab based on KIR genotypes
Barbara Manzanares-Martin, Arancha Cebrián Aranda, Laura del Puerto-Nevado, Rafael González, Sonia Solanes, Maria Auxiliadora Gómez-España, Jesús García-Foncillas, Enrique Aranda

Journal for ImmunoTherapy of Cancer Apr 2021, 9 (4) e001705; DOI: 10.1136/jitc-2020-001705
Anti-GD2 antibody dinutuximab inhibits triple-negative breast tumor growth by targeting GD2⁺ breast cancer stem-like cells
Stanley Ly, Vivek Anand, Fouad El-Dana, Khoa Nguyen, Yiming Cai, Shirong Cai, Helen Piwnica-Worms, Debasish Tripathy, Aysegul A Sahin, Michael Andreeff, Venkata Lokesh Battula

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001197; DOI: 10.1136/jitc-2020-001197
Therapeutic afucosylated monoclonal antibody and bispecific T-cell engagers for T-cell acute lymphoblastic leukemia
Daniele Caracciolo, Caterina Riillo, Andrea Ballerini, Giuseppe Gaipa, Ludovic Lhermitte, Marco Rossi, Cirino Botta, Eugénie Duroyon, Katia Grillone, Maria Eugenia Gallo Cantafio, Chiara Buracchi, Greta Alampi, Alessandro Gulino, Beatrice Belmonte, Francesco Conforti, Gaetanina Golino, Giada Juli, Emanuela Altomare, Nicoletta Polerà, Francesca Scionti, Mariamena Arbitrio, Michelangelo Iannone, Massimo Martino, Pierpaolo Correale, Gabriella Talarico, Andrea Ghelli Luserna di Rorà, Anna Ferrari, Daniela Concolino, Simona Sestito, Licia Pensabene, Antonio Giordano, Markus Hildinger, Maria Teresa Di Martino, Giovanni Martinelli, Claudio Tripodo, Vahid Asnafi, Andrea Biondi, Pierosandro Tagliaferri, Pierfrancesco Tassone

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e002026; DOI: 10.1136/jitc-2020-002026

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