Antigens

Self-assembly nanovaccine containing TLR7/8 agonist and STAT3 inhibitor enhances tumor immunotherapy by augmenting tumor-specific immune response
Lele Zhang, Jiacheng Huang, Xiaona Chen, Caixu Pan, Yong He, Rong Su, Danjing Guo, Shengyong Yin, Shuai Wang, Lin Zhou, Jianxiang Chen, Shusen Zheng, Yiting Qiao

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e003132; DOI: 10.1136/jitc-2021-003132
Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro
Aneta Ledererova, Lenka Dostalova, Veronika Kozlova, Helena Peschelova, Adriana Ladungova, Martin Culen, Tomas Loja, Jan Verner, Sarka Pospisilova, Michal Smida, Veronika Mancikova

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002352; DOI: 10.1136/jitc-2021-002352
Immunization with short peptide particles reveals a functional CD8⁺ T-cell neoepitope in a murine renal carcinoma model
Xuedan He, Shiqi Zhou, Melissa Dolan, Yuhao Shi, Jianxin Wang, Breandan Quinn, Dushyant Jahagirdar, Wei-Chiao Huang, Moriya Tsuji, Roberto Pili, Fumito Ito, Joaquin Ortega, Scott I Abrams, John M L Ebos, Jonathan F Lovell

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003101; DOI: 10.1136/jitc-2021-003101
Protein citrullination as a source of cancer neoantigens
Hiroyuki Katayama, Makoto Kobayashi, Ehsan Irajizad, Alejandro M Sevillano, Nikul Patel, Xiangying Mao, Leona Rusling, Jody Vykoukal, Yining Cai, Fuchung Hsiao, Chuan-Yih Yu, James Long, Jinsong Liu, Franscisco Esteva, Johannes Fahrmann, Sam Hanash

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002549; DOI: 10.1136/jitc-2021-002549
Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer
Tianhang Zhai, Chao Wang, Yifeng Xu, Weifeng Huang, Zhijun Yuan, Tao Wang, Shuang Dai, Shaogang Peng, Tuling Pang, Wenchao Jiang, Yuhua Huang, Yuefeng Zou, Yingda Xu, Joanne Sun, Xinjiang Gong, Jinping Zhang, Andy Tsun, Bin Li, Xiaoniu Miao

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002131; DOI: 10.1136/jitc-2020-002131
Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy
Hannah Reimann, Andrew Nguyen, J Zachary Sanborn, Charles J Vaske, Stephen C Benz, Kayvan Niazi, Shahrooz Rabizadeh, Patricia Spilman, Andreas Mackensen, Matthias Ruebner, Alexander Hein, Matthias W Beckmann, Edith D van der Meijden, Judith Bausenwein, Sascha Kretschmann, Marieke Griffioen, Jeffrey Schlom, James L Gulley, Karin L Lee, Duane H Hamilton, Patrick Soon-Shiong, Peter A Fasching, Anita N. Kremer

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002605; DOI: 10.1136/jitc-2021-002605
TGM4: an immunogenic prostate-restricted antigen
Zoila A Lopez-Bujanda, Aleksandar Obradovic, Thomas R Nirschl, Laura Crowley, Rodney Macedo, Alexandros Papachristodoulou, Timothy O’Donnell, Uri Laserson, Jelani C Zarif, Ran Reshef, Tiezheng Yuan, Mithil K Soni, Emmanuel S Antonarakis, Michael C Haffner, H Benjamin Larman, Michael M Shen, Pawel Muranski, Charles G Drake

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e001649; DOI: 10.1136/jitc-2020-001649
First immunotherapeutic CAR-T cells against the immune checkpoint protein HLA-G
François Anna, Elodie Bole-Richard, Joel LeMaoult, Marie Escande, Martin Lecomte, Jean-Marie Certoux, Philippe Souque, Francine Garnache, Olivier Adotevi, Pierre Langlade-Demoyen, Maria Loustau, Julien Caumartin

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001998; DOI: 10.1136/jitc-2020-001998
IL-15 mediated expansion of rare durable memory T cells following adoptive cellular therapy
Karan Kohli, Lu Yao, Theodore Scott Nowicki, Shihong Zhang, Ralph Graeme Black, Brett A Schroeder, Erik A Farrar, Jianhong Cao, Heather Sloan, Dawn Stief, Lee D Cranmer, Michael J Wagner, Douglas S Hawkins, Venu G Pillarisetty, Antoni Ribas, Jean Campbell, Robert H Pierce, Edward Y Kim, Robin L Jones, Stanley R Riddell, Cassian Yee, Seth M Pollack

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002232; DOI: 10.1136/jitc-2020-002232
T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia
Sayed Shahabuddin Hoseini, Mallika Vadlamudi, Madelyn Espinosa-Cotton, Hoa Tran, Yi Feng, Hong-fen Guo, Hong Xu, Irene Cheung, Nai-Kong V Cheung

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002509; DOI: 10.1136/jitc-2021-002509

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