cell engineering

IL-15 mediated expansion of rare durable memory T cells following adoptive cellular therapy
Karan Kohli, Lu Yao, Theodore Scott Nowicki, Shihong Zhang, Ralph Graeme Black, Brett A Schroeder, Erik A Farrar, Jianhong Cao, Heather Sloan, Dawn Stief, Lee D Cranmer, Michael J Wagner, Douglas S Hawkins, Venu G Pillarisetty, Antoni Ribas, Jean Campbell, Robert H Pierce, Edward Y Kim, Robin L Jones, Stanley R Riddell, Cassian Yee, Seth M Pollack

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002232; DOI: 10.1136/jitc-2020-002232
CBLB ablation with CRISPR/Cas9 enhances cytotoxicity of human placental stem cell-derived NK cells for cancer immunotherapy
Xuan Guo, Tanel Mahlakõiv, Qian Ye, Srinivas Somanchi, Shuyang He, Hemlata Rana, Andrea DiFiglia, Joseph Gleason, William van der Touw, Robert Hariri, Xiaokui Zhang

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001975; DOI: 10.1136/jitc-2020-001975
Designed improvement to T-cell immunotherapy by multidimensional single cell profiling
Irfan N Bandey, Jay R T Adolacion, Gabrielle Romain, Melisa Martinez Paniagua, Xingyue An, Arash Saeedi, Ivan Liadi, Zheng You, Rasindu B Rajanayake, Patrick Hwu, Harjeet Singh, Laurence JN Cooper, Navin Varadarajan

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001877; DOI: 10.1136/jitc-2020-001877
Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model
Tereza Andreou, Jennifer Williams, Rebecca J Brownlie, Robert J Salmond, Erica Watson, Gary Shaw, Alan Melcher, Heiko Wurdak, Susan C Short, Mihaela Lorger

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001143; DOI: 10.1136/jitc-2020-001143
Mesenchymal stem cells and oncolytic viruses: joining forces against cancer
Rafael Moreno

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e001684; DOI: 10.1136/jitc-2020-001684
Deletion of Cbl-b inhibits CD8⁺ T-cell exhaustion and promotes CAR T-cell function
Jitendra Kumar, Ritesh Kumar, Amir Kumar Singh, Elviche L Tsakem, Mahesh Kathania, Matthew J Riese, Arianne L Theiss, Marco L Davila, K Venuprasad

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001688; DOI: 10.1136/jitc-2020-001688
Letter to the editor: Checking the pulse of adoptive cell therapy for solid tumors. Thoughts from the abstracts submitted to the 35th Annual Meeting of the Society for the Immunotherapy of Cancer (SITC 2020)
Martina Markovska, Francesco Marincola

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e002216; DOI: 10.1136/jitc-2020-002216
Blockade of AIM2 inflammasome or α1-AR ameliorates IL-1β release and macrophage-mediated immunosuppression induced by CAR-T treatment
Dan Liu, Xiyue Xu, Yulian Dai, Xuan Zhao, Shunshun Bao, Wen Ma, Li Zha, Shuci Liu, Yuchen Liu, Junnian Zheng, Ming Shi

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001466; DOI: 10.1136/jitc-2020-001466
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune effector cell-related adverse events
Marcela V Maus, Sara Alexander, Michael R Bishop, Jennifer N Brudno, Colleen Callahan, Marco L Davila, Claudia Diamonte, Jorg Dietrich, Julie C Fitzgerald, Matthew J Frigault, Terry J Fry, Jennifer L Holter-Chakrabarty, Krishna V Komanduri, Daniel W Lee, Frederick L Locke, Shannon L Maude, Philip L McCarthy, Elena Mead, Sattva S Neelapu, Tomas G Neilan, Bianca D Santomasso, Elizabeth J Shpall, David T Teachey, Cameron J Turtle, Tom Whitehead, Stephan A Grupp

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001511; DOI: 10.1136/jitc-2020-001511
In vivo therapeutic effects of affinity-improved-TCR engineered T-cells on HBV-related hepatocellular carcinoma
Qi Liu, Ye Tian, Yanyan Li, Wei Zhang, Wenxuan Cai, Yaju Liu, Yuefei Ren, Zhaoduan Liang, Peipei Zhou, Yajing Zhang, Yifeng Bao, Yi Li

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001748; DOI: 10.1136/jitc-2020-001748

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