cell engineering

CXCL10 and Nrf2-upregulated mesenchymal stem cells reinvigorate T lymphocytes for combating glioblastoma
Jiaji Mao, Jianing Li, Junwei Chen, Qin Wen, Minghui Cao, Fang Zhang, Baoxun Li, Qinyuan Zhang, Zhe Wang, Jingzhong Zhang, Jun Shen

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007481; DOI: 10.1136/jitc-2023-007481
Knockout of the inhibitory receptor TIGIT enhances the antitumor response of ex vivo expanded NK cells and prevents fratricide with therapeutic Fc-active TIGIT antibodies
Md Faqrul Hasan, Amanda R Campbell, Tayler J Croom-Perez, Jeremiah L Oyer, Thomas A Dieffenthaller, Liza D Robles-Carrillo, Catherine A Cash, Jonathan E Eloriaga, Sanjana Kumar, Brendan W Andersen, Meisam Naeimi Kararoudi, Brian P Tullius, Dean A Lee, Alicja J Copik

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007502; DOI: 10.1136/jitc-2023-007502
HER2 and HLA-A*02 dual CAR-T cells utilize LOH in a NOT logic gate to address on-target off-tumor toxicity
David Bassan, Leehee Weinberger, Jason Yi, Tanya Kim, Michael R Weist, Gregor B Adams, Orit Foord, Neta Chaim, Sarit Tabak, Nir Bujanover, Yael Lopesco, Kristina Vucci, Caitlin Schnair, Limor Levy-Knafo, Richard L Kendall, Frank J Calzone, Adi Sharbi-Yunger

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007426; DOI: 10.1136/jitc-2023-007426
BiTE secretion by adoptively transferred stem-like T cells improves FRα+ ovarian cancer control
A J Robert McGray, Jessie L Chiello, Takemasa Tsuji, Mark Long, Kathryn Maraszek, Nicole Gaulin, Spencer R Rosario, Suzanne M Hess, Scott I Abrams, Danuta Kozbor, Kunle Odunsi, Emese Zsiros

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006863; DOI: 10.1136/jitc-2023-006863
Engineering second-generation TCR-T cells by site-specific integration of TRAF-binding motifs into the CD247 locus
Sangjoon Lah, Segi Kim, In Kang, Hyojin Kim, Cedric Hupperetz, Hyuncheol Jung, Hyeong Ryeol Choi, Young-Ho Lee, Hyeon-Ki Jang, Sangsu Bae, Chan Hyuk Kim

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e005519; DOI: 10.1136/jitc-2022-005519
Harnessing novel strategies and cell types to overcome immune tolerance during adoptive cell therapy in cancer
Shi Yong Neo, Shengli Xu, Joni Chong, Kong-Peng Lam, Jing Wu

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006434; DOI: 10.1136/jitc-2022-006434
Tumor-infiltrating lymphocytes mediate complete and durable remission in a patient with NY-ESO-1 expressing prostate cancer
Julia Karbach, Dragan Kiselicki, Kathrin Brand, Claudia Wahle, Evgueni Sinelnikov, Dirk Gustavus, Hans Hoffmeister, Hans-Bernd Prisack, Akin Atmaca, Elke Jäger

Journal for ImmunoTherapy of Cancer Jan 2023, 11 (1) e005847; DOI: 10.1136/jitc-2022-005847
Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study
Sophie Papa, Antonella Adami, Michael Metoudi, Richard Beatson, Molly Sarah George, Daniela Achkova, Evangelia Williams, Sefina Arif, Fiona Reid, Maria Elstad, Nicholas Beckley-Hoelscher, Abdel Douri, Marc Delord, Mike Lyne, Dharshene Shivapatham, Christopher Fisher, Andrew Hope, Sakina Gooljar, Arindam Mitra, Linda Gomm, Cienne Morton, Rhonda Henley-Smith, Selvam Thavaraj, Alice Santambrogio, Cynthia Andoniadou, Sarah Allen, Victoria Gibson, Gary J R Cook, Ana C Parente-Pereira, David M Davies, Farzin Farzaneh, Anna Schurich, Teresa Guerrero-Urbano, Jean-Pierre Jeannon, James Spicer, John Maher

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e007162; DOI: 10.1136/jitc-2023-007162
Blockade of AIM2 inflammasome or α1-AR ameliorates IL-1β release and macrophage-mediated immunosuppression induced by CAR-T treatment
Dan Liu, Xiyue Xu, Yulian Dai, Xuan Zhao, Shunshun Bao, Wen Ma, Li Zha, Shuci Liu, Yuchen Liu, Junnian Zheng, Ming Shi

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001466; DOI: 10.1136/jitc-2020-001466
Letter to the editor: Checking the pulse of adoptive cell therapy for solid tumors. Thoughts from the abstracts submitted to the 35th Annual Meeting of the Society for the Immunotherapy of Cancer (SITC 2020)
Martina Markovska, Francesco Marincola

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e002216; DOI: 10.1136/jitc-2020-002216

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