chimeric antigen

Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity
Congcong Zhang, Jasmin Röder, Anne Scherer, Malena Bodden, Jordi Pfeifer Serrahima, Anita Bhatti, Anja Waldmann, Nina Müller, Pranav Oberoi, Winfried S Wels

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002980; DOI: 10.1136/jitc-2021-002980
Conditioned CAR-T cells by hypoxia-inducible transcription amplification (HiTA) system significantly enhances systemic safety and retains antitumor efficacy
Huan He, Qibin Liao, Chen Zhao, Cuisong Zhu, Meiqi Feng, Zhuoqun Liu, Lang Jiang, Linxia Zhang, Xiangqing Ding, Min Yuan, Xiaoyan Zhang, Jianqing Xu

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002755; DOI: 10.1136/jitc-2021-002755
Humoral immunogenicity of the seasonal influenza vaccine before and after CAR-T-cell therapy: a prospective observational study
Carla S Walti, Andrea N Loes, Kiel Shuey, Elizabeth M Krantz, Jim Boonyaratanakornkit, Jacob Keane-Candib, Tillie Loeffelholz, Caitlin R Wolf, Justin J Taylor, Rebecca A Gardner, Damian J Green, Andrew J Cowan, David G Maloney, Cameron J Turtle, Steven A Pergam, Helen Y Chu, Jesse D Bloom, Joshua A Hill

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003428; DOI: 10.1136/jitc-2021-003428
4-1BB and optimized CD28 co-stimulation enhances function of human mono-specific and bi-specific third-generation CAR T cells
Emiliano Roselli, Justin C Boucher, Gongbo Li, Hiroshi Kotani, Kristen Spitler, Kayla Reid, Estelle V Cervantes, Yannick Bulliard, Nhan Tu, Sae Bom Lee, Bin Yu, Frederick L Locke, Marco L Davila

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003354; DOI: 10.1136/jitc-2021-003354
Selectively targeting myeloid-derived suppressor cells through TRAIL receptor 2 to enhance the efficacy of CAR T cell therapy for treatment of breast cancer
Saisha A Nalawade, Paul Shafer, Pradip Bajgain, Mary K McKenna, Arushana Ali, Lauren Kelly, Jarrett Joubert, Stephen Gottschalk, Norihiro Watanabe, Ann Leen, Robin Parihar, Juan Fernando Vera Valdes, Valentina Hoyos

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003237; DOI: 10.1136/jitc-2021-003237
T-cell intrinsic Toll-like receptor signaling: implications for cancer immunotherapy and CAR T-cells
Yasmin Nouri, Robert Weinkove, Rachel Perret

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003065; DOI: 10.1136/jitc-2021-003065
Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants
Enrique Conde, Enric Vercher, Marta Soria-Castellano, Jesús Suarez-Olmos, Uxua Mancheño, Edurne Elizalde, M Luis Rodriguez, Javier Glez-Vaz, Noelia Casares, Estefanía Rodríguez-García, Mirja Hommel, Gloria González-Aseguinolaza, Iratxe Uranga-Murillo, Julian Pardo, Gorka Alkorta, Ignacio Melero, Juan Lasarte, Sandra Hervas-Stubbs

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003351; DOI: 10.1136/jitc-2021-003351
αPD-1-mesoCAR-T cells partially inhibit the growth of advanced/refractory ovarian cancer in a patient along with daily apatinib
Juemin Fang, Na Ding, Xianling Guo, Yan Sun, Zhiwei Zhang, Bailu Xie, Zhong Li, Hui Wang, Wei Mao, Zhicai Lin, Fei Qin, Min Yuan, Wenqi Chu, Huanlong Qin, Qijun Qian, Qing Xu

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e001162; DOI: 10.1136/jitc-2020-001162
First report of CART treatment in AL amyloidosis and relapsed/refractory multiple myeloma
Aina Oliver-Caldes, Raquel Jiménez, Marta Español-Rego, Maria Teresa Cibeira, Valentín Ortiz-Maldonado, Luis F Quintana, Paola Castillo, Francesca Guijarro, Natalia Tovar, Mercedes Montoro, Daniel Benitez-Ribas, Alex Bataller, E Azucena González-Navarro, Joan Cid, Miquel Lozano, Lorena Perez-Amill, Beatriz Martin-Antonio, Mari-Pau Mena, David F Moreno, Luis Gerardo Rodríguez-Lobato, Josep Maria Campistol, Gonzalo Calvo, Joan Bladé, Laura Rosiñol, Manel Juan, Mariona Pascal, Alvaro Urbano-Ispizua, Carlos Fernández de Larrea

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003783; DOI: 10.1136/jitc-2021-003783
Challenges and next steps in the advancement of immunotherapy: summary of the 2018 and 2020 National Cancer Institute workshops on cell-based immunotherapy for solid tumors
Laura K Fogli, Rosemarie Aurigemma, Connie L Sommers, Anju Singh, Kasia Bourcier, Marc S Ernstoff

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e003048; DOI: 10.1136/jitc-2021-003048

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