costimulatory and inhibitory T-cell receptors

Immune checkpoint inhibitor-associated celiac disease
Yousef R Badran, Angela Shih, Donna Leet, Meghan J Mooradian, Alexandra Coromilas, Jonathan Chen, Marina Kem, Hui Zheng, Jennifer Borowsky, Joseph Misdraji, Mari Mino-Kenudson, Michael Dougan

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000958; DOI: 10.1136/jitc-2020-000958
BT7480, a novel fully synthetic Bicycle tumor-targeted immune cell agonist™ (Bicycle TICA™) induces tumor localized CD137 agonism
Kristen Hurov, Johanna Lahdenranta, Punit Upadhyaya, Eric Haines, Heather Cohen, Elizabeth Repash, Drasti Kanakia, Jun Ma, Julia Kristensson, Fanglei You, Carly Campbell, David Witty, Mike Kelly, Stephen Blakemore, Phil Jeffrey, Kevin McDonnell, Philip Brandish, Nicholas Keen

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e002883; DOI: 10.1136/jitc-2021-002883
TIGIT/CD155 axis mediates resistance to immunotherapy in patients with melanoma with the inflamed tumor microenvironment
Shusuke Kawashima, Takashi Inozume, Masahito Kawazu, Toshihide Ueno, Joji Nagasaki, Etsuko Tanji, Akiko Honobe, Takehiro Ohnuma, Tatsuyoshi Kawamura, Yoshiyasu Umeda, Yasuhiro Nakamura, Tomonori Kawasaki, Yukiko Kiniwa, Osamu Yamasaki, Satoshi Fukushima, Yuzuru Ikehara, Hiroyuki Mano, Yutaka Suzuki, Hiroyoshi Nishikawa, Hiroyuki Matsue, Yosuke Togashi

Journal for ImmunoTherapy of Cancer May 2022, 9 (11) e003134; DOI: 10.1136/jitc-2021-003134
Novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade
Seongju Jeong, Eunyoung Park, Hyung-Don Kim, Eunsil Sung, Hyunjoo Kim, Jaehyoung Jeon, Youngkwang Kim, Ui-jung Jung, Yong-Gyu Son, Youngeun Hong, Hanbyul Lee, Shinai Lee, Yangmi Lim, Jonghwa Won, Minwoo Jeon, Shin Hwang, Lei Fang, Wenqing Jiang, Zhengyi Wang, Eui-Cheol Shin, Su-Hyung Park, Jaeho Jung

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002428; DOI: 10.1136/jitc-2021-002428
Chimeric non-antigen receptors in T cell-based cancer therapy
Jitao Guo, Andrew Kent, Eduardo Davila

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002628; DOI: 10.1136/jitc-2021-002628
B7 score and T cell infiltration stratify immune status in prostate cancer
Qianghua Zhou, Kaiwen Li, Yiming Lai, Kai Yao, Qiong Wang, Xiangyu Zhan, Shirong Peng, Wenli Cai, Wei Yao, Xingxing Zang, Kewei Xu, Jian Huang, Hai Huang

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002455; DOI: 10.1136/jitc-2021-002455
Combinatorial immunotherapy induces tumor-infiltrating CD8⁺ T cells with distinct functional, migratory, and stem-like properties
Natalija Van Braeckel-Budimir, Joseph Samuel Dolina, Jie Wei, Xiao Wang, Shih-Hsun Chen, Pamela Santiago, Guanghuan Tu, Luca Micci, Amir A Al-Khami, Sophia Pfister, Sripad Ram, Purnima Sundar, Graham Thomas, Hua Long, Wenjing Yang, Shobha Potluri, Shahram Salek-Ardakani

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003614; DOI: 10.1136/jitc-2021-003614
Costimulation of γδTCR and TLR7/8 promotes Vδ2 T-cell antitumor activity by modulating mTOR pathway and APC function
Huaishan Wang, Hui Chen, Shujing Liu, Jie Zhang, Hezhe Lu, Rajasekharan Somasundaram, Robin Choi, Gao Zhang, Lingling Ou, John Scholler, Shifu Tian, Liyun Dong, Guo Yeye, Lili Huang, Thomas Connelly, Ling Li, Alexander Huang, Tara C Mitchell, Yi Fan, Carl H June, Gordon B Mills, Wei Guo, Meenhard Herlyn, Xiaowei Xu

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003339; DOI: 10.1136/jitc-2021-003339
TIGIT-CD226-PVR axis: advancing immune checkpoint blockade for cancer immunotherapy
Eugene Y Chiang, Ira Mellman

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e004711; DOI: 10.1136/jitc-2022-004711
Prospective real-world study on the pharmacokinetics of pembrolizumab in patients with solid tumors
Daan P. Hurkmans, Sebastiaan D.T. Sassen, Karlijn de Joode, Lisanne Putter, Edwin A. Basak, Annemarie J.M. Wijkhuijs, Markus Joerger, Reno Debets, Birgit C.P. Koch, Cor H. Van der Leest, Marco W.J. Schreurs, Astrid A.M. van der Veldt, Joachim G.J.V. Aerts, Ron H.J. Mathijssen, Stijn L.W. Koolen

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002344; DOI: 10.1136/jitc-2021-002344

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